First thing is anyone who isn’t measuring adblocking regularly is asking for trouble. I know some publishers that have very low adblocking numbers and so have decided to not even watch it. I think that’s a mistake. Keep measuring!
The second thing is trying to unblock the blockers (and serve them ads without their permission s in my opinion a big mistake. I do think it’s an opportunity to connect to those users and explain the value exchange (ads = free content) and to try to find a common ground. The result may be subscriptions or asking to be whitelisted in exchange for a lighter ad experience. These users are your audience. It only makes sense to engage with them to figure this out.